Variant of Concern Reports
A comprehensive database of reports on SARS-CoV-2 lineages designated as Variants of Concern by global health organizations.
Omicron
CirculatingCharacterized by an unprecedented number of spike mutations, leading to significant immune evasion and rapid global spread. Spawned numerous successful sub-lineages (BA.2, BA.5, XBB).
Designated
November 26, 2021
Key Mutations
Delta
Previously CirculatingMarked by significantly increased transmissibility compared to previous variants, leading to a major global wave of infections. Associated with higher risk of hospitalization.
Designated
May 11, 2021
Key Mutations
Gamma
Previously CirculatingFirst identified in Brazil, this variant raised concerns due to its ability to evade immunity from previous infections. Carried key mutations like E484K and N501Y.
Designated
January 11, 2021
Key Mutations
Beta
Previously CirculatingFirst detected in South Africa, this variant showed significant immune evasion capabilities, reducing the efficacy of some vaccines and monoclonal antibody treatments.
Designated
December 18, 2020
Key Mutations
Alpha
Previously CirculatingOne of the first major VOCs, first identified in the UK. It was characterized by increased transmissibility and a higher risk of mortality compared to the ancestral strain.
Designated
December 18, 2020
Key Mutations
About VOC Designations
World Health Organization
Variants of Concern (VOCs) are designated by global health organizations like the WHO when a variant demonstrates increased transmissibility, virulence, or reduced effectiveness of public health measures.
The Pango nomenclature system provides the standardized naming convention used to track and communicate about these variants across the global scientific community.